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Without telling Emily or her parents anything, Bill decides with Zoe to test on Emily the biological weapon he hopes to be able to use against the aliens. Catherine, for her part, has had difficulty managing her grief since Mokrani's death. She now has only one thing on her mind: to find out who Bill Ward is and find him. Sophia is ready to help him, but Nathan hesitates.

Catherine, Sophia and Nathan make their way to London, accompanied by Victor, a survivor encountered by chance. Along the way, the dangers multiply. Sacha's feelings towards Emily intensify and the young man's behavior becomes more and more disturbing. Feeling threatened, Bill is forced to flee.

Pakļauti izslēgšanas draudiem, Jumiulaks un Džesija pēc mācību gada beigām turpina apmeklēt savu tukšo vidusskolu. Nezinot par vasaras brīvlaiku, viņi uzskata, ka tiek pārbaudīti, un mēģina mācīt viens otru. Viņi saprot savu kļūdu un nodara postījumus skolā. Korvo un Terija ierodas junioru koledžā, bet Terija nošauj Korvo ar staru lielgabalu, kas padara viņu vēl dumjāku.

Jodie's celebrity is on the rise and M.O.D.O.K. plans on winning her back from her new boyfriend, the superhero Wonder Man. Jodie and her publicist invite M.O.D.O.K. to a party, knowing his temper will bring publicity. M.O.D.O.K. provokes Wonder Man into attacking him at the party and is kicked out. Wonder Man leaves Jodie when he sees she’s only using him for exposure. Melissa and Lou bond over their disappointment in their parents. M.O.D.O.K. and Jodie have sex when he goes to apologize, and it is revealed who exactly was behind her publicist’s actions.

Bill joins the military group formed by Ethan, Dominic and Michael. The three men hold a young alien hostage, Isla. Catherine, Sophia and Nathan continue to search for Bill. Adina, and the aliens also set out to find Bill. Chloe accuses the blow when she realizes that Sacha killed Ash. She suggests to her increasingly unstable son to run away with her.

At the university, Sophia watches the videos recorded by Dylan, a young man they found dead, while Catherine focuses on the algorithms he left behind and which decipher the behavior of robots. Thanks to Bill's intervention, Isla manages to flee and join her family.

Emily agrees to help Bill test her for the virus, but soon experiences serious side effects. Sacha, who has secretly followed the group to stay close to Emily, tries to remove her from the group. For their part, Catherine, Sophia and Nathan set out again in search of Bill Ward.

Conrad comes under fire when a former patient files a malpractice lawsuit against him, putting Bell in a difficult position with Red Rock. When Devon discovers that his VIP patient has a life-threatening brain condition, the doctors ban together to perform a risky surgery. Meanwhile, Mina discovers that Adaku has a dangerous heart condition that puts her and the baby at risk, and Kyle forms a personal relationship with a patient.

On Devon's last day as an intern, he and Conrad are faced with a moral dilemma over a suicidal patient who is in need of a liver transplant. When Bell discovers that Cain is keeping braindead patients alive in order to boost his survival rates and add to Red Rock's profits, he decides to take matters into his own hands. Meanwhile, Adaku goes into early labor, causing a strain on her heart and Mina is left in doubt over how to best handle her care.

After being terminated from Chastain, Conrad has difficulty figuring out his next step and distracts himself by accompanying a patient on a zero-gravity adventure. In his first move as the new Chief of Surgery, Cain puts the doctors on a commission-based pay system, which causes Devon’s new intern to agree to a procedure before weighing the risks. Meanwhile, Mina struggles with taking care of Adaku’s baby and Bell’s supplement company get its big break.

Dr. Addison Forbes Montgomery returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents. Meredith has a decision to make; Link confides in Teddy.

Richard recruits Meredith and Bailey to help him launch a new program. Addison's patient has complications from a procedure. Jo helps a woman who goes into premature labor.

The doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home. In Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study.

Just when Ryan agrees to talk it out with his dad, Greg Tanner makes an unexpected visit to Station 19, leaving Ryan and others confused. In an effort to connect with his crew, Captain Sullivan enlists the help of an unlikely source for some bonding tips.

As the team gathers for a Friendsgiving celebration at Dean's, a violent windstorm touches down in Seattle. As the storm picks up speed, creating dangerous fire conditions, the crew must put the festivities on hold and report for duty, leaving some of them in a life-threatening situation.

Pagājuši pieci gadi, kopš Ketrīna nošāva savu bijušo vīru, un Sjūzena, Lineta, Brī un Gabija stāvēja plecu pie pleca, lai viņu aizsargātu.

Noslēpumi turpina atklāties: Lineta atklāj, ka viņas dēlam Porteram ir maigāka puse, kas viņu patīkami pārsteidz; Gabija cenšas ar humoru noslēpt savu pagrimumu sabiedrības acīs; Sjūzenas dzīvē pienācis brīdis, kad viņas vīriešiem beidzot jāsatiekas. Tikmēr Brī sāk izjust pieaugošo spriedzi, cenšoties līdzsvarot laulību un karjeru; Edijai atkal tiek atgādināts, cik naidīgi spēj būt Vistērijas ielas kaimiņi, bet aizdomīgā Maklaskija kundze metas uz vienu roku ar Ketrīnu, lai kopīgi noskaidrotu vairāk par viņu noslēpumaino jauno kaimiņu Deivu.

It's Thanksgiving and while Meredith faces travel complications, due to the weather, Nick steps in to help – in more ways than one. Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

With Chastain on the verge of shutting down due to the sale by Red Rock, Conrad tries a last-ditch effort to save the hospital and the doctors plan for their next career moves. Meanwhile, on their last day, the whole staff must work together to save Nic’s life after she is injured by a deranged patient.

Brī meita Daniela atgriežas Vistērijas ielā un uzreiz nonāk nežēlīgā kritikas lavīnā, savukārt Gabija un Sjūzena metas īstā sieviešu ķīviņā.

Vistērijas ielas dāmas skaudīgi noraugās uz Brī pavārgrāmatu un viņas biznesa panākumiem, savukārt Lineta netur sveci zem pūra un izsaka viedokli par Brī mārketinga stratēģiju. Tikmēr Maiks jūtas atstumts un raizējas, ka viņa klātbūtne dēla dzīvē ir pārāk nenozīmīga.

Dr. Megana Hanta bija augstas klases neiroķirurģe savas karjeras virsotnē. Viņas pasaule tiek sagriezta kājām gaisā, kad postošs negadījums pieliek punktu viņas iespējām darboties operāciju zālē. Megana atsāk savu karjeru, veicot medicīnisko ekspertīzi, ar apņēmību atrisināt mīklas par to, kurš vai kas nogalinājis upurus.

Dr. Megana Hanta bija augstas klases neiroķirurģe savas karjeras virsotnē. Viņas pasaule tiek sagriezta kājām gaisā, kad postošs negadījums pieliek punktu viņas iespējām darboties operāciju zālē. Megana atsāk savu karjeru, veicot medicīnisko ekspertīzi, ar apņēmību atrisināt mīklas par to, kurš vai kas nogalinājis upurus.

Dr. Megana Hanta bija augstas klases neiroķirurģe savas karjeras virsotnē. Viņas pasaule tiek sagriezta kājām gaisā, kad postošs negadījums pieliek punktu viņas iespējām darboties operāciju zālē. Megana atsāk savu karjeru, veicot medicīnisko ekspertīzi, ar apņēmību atrisināt mīklas par to, kurš vai kas nogalinājis upurus.

Sieviešu-šķiršanās advokāšu komanda pamet vīriešu dominētu firmu, lai izveidotu savu spēkpilno praksi. Kvēlās, ģeniālās un emocionāli sarežģītās sievietes orientējas augsta riska šķiršanās lietās, skandalozos noslēpumos un mainīgās aliansēs kā tiesu zālē, tā savās rindās. Pasaulē, kur nauda runā un mīlestība ir kaujas lauks, šīs sievietes ne tikai spēlē spēli, bet arī to maina.

Slepenu nolūku vadīts, Deivs pārliecina Sjūzenu sarīkot pārsteiguma dzimšanas dienas ballīti Maklaskija kundzei; Džeksons vēlas nopietnākas attiecības ar Sjūzenu, bet Maklaskija kundze liek visiem kaimiņiem apšaubīt viņas veselo saprātu.

Gabija ir sajūsmā, kad Karlosa klients izsaka piedāvājumu, no kura viņi nespēj atteikties, taču negaidīts atklājums liek viņai sākt šaubīties. Lineta sāk aizdomāties, vai Toms viņu nekrāpj, bet Sjūzena pēc šķiršanās no Džeksona cenšas viņu pārsteigt, taču atklāj, ka pati kļuvusi par pārsteiguma upuri. Tikmēr Brī un Ketrīnas savstarpējā saikne kļūst arvien ciešāka, un Maklaskija kundze iesaista savu māsu, lai kopīgi uzzinātu jebkādu neglaimojošu informāciju par Deivu.

Beisbola spēlētājs Džastins uzzina, ka viņu medī bijušā spēlētāja spoks. Spoks meklē atriebības iespējas, lai ieriebtu trenerim, kas it kā vainojams viņa nāvē.

Dr. Megana Hanta bija augstas klases neiroķirurģe savas karjeras virsotnē. Viņas pasaule tiek sagriezta kājām gaisā, kad postošs negadījums pieliek punktu viņas iespējām darboties operāciju zālē. Megana atsāk savu karjeru, veicot medicīnisko ekspertīzi, ar apņēmību atrisināt mīklas par to, kurš vai kas nogalinājis upurus.